U.S. researchers gave the first shot to the first person in a test of an experimental coronavirus vaccine Monday 맥스카지노� leading off a worldwide hunt for protection even as the pandemic surges.With a careful jab in a healthy volunteer맥스카지노�s arm, scientists at the Kaiser Permanente Washington Research Institute in Seattle begin an anxiously awaited first-stage study of a potential COVID-19 vaccine developed in record time after the new virus exploded from China and fanned across the globe.맥스카지노�We맥스카지노�re team coronavirus now,맥스카지노� Kaiser Permanente study leader Dr. Lisa Jackson said on the eve of the experiment. 맥스카지노�Everyone wants to do what they can in this emergency.맥스카지노�The Associated Press observed as the study맥스카지노�s first participant, an operations manager at a small tech company, received the injection inside an exam room. Several others were next in line for a test that will ultimately give 45 volunteers two doses, a month apart.맥스카지노�We all feel so helpless. This is an amazing opportunity for me to do something,맥스카지노� said Jennifer Haller, 43, of Seattle.She's the mother of two teenagers and 맥스카지노�they think it's cool맥스카지노� that she's taking part in the study.Monday맥스카지노�s milestone marked just the beginning of a series of studies in people needed to prove whether the shots are safe and could work. Even if the research goes well, a vaccine wouldn맥스카지노�t be available for widespread use for 12 to 18 months, said Dr. Anthony Fauci of the U.S. National Institutes of Health. That맥스카지노�s still important if the virus becomes a long-term threat.This vaccine candidate, code-named mRNA-1273, was developed by the NIH and Massachusetts-based biotechnology company Moderna Inc. There맥스카지노�s no chance participants could get infected from the shots because they don맥스카지노�t contain the coronavirus itself.It맥스카지노�s not the only potential vaccine in the pipeline. Dozens of research groups around the world are racing to create a vaccine against COVID-19. Another candidate, made by Inovio Pharmaceuticals, is expected to begin its own safety study -- in the U.S., China and South Korea -- next month.The Seattle experiment got underway days after the World Health Organization declared the new virus outbreak a pandemic because of its rapid global spread, infecting more than 169,000 people and killing more than 6,500.COVID-19 has upended the world맥스카지노�s social and economic fabric since China first identified the virus in January, with regions shuttering schools and businesses, restricting travel, canceling entertainment and sporting events, and encouraging people to stay away from each other.Starting what scientists call a first-in-humans study is a momentous occasion for scientists, but Jackson described her team맥스카지노�s mood as 맥스카지노�subdued.맥스카지노� They맥스카지노�ve been working round-the-clock readying the research in a part of the U.S. struck early and hard by the virus.Still, 맥스카지노�going from not even knowing that this virus was out there ... to have any vaccine맥스카지노� in testing in about two months is unprecedented, Jackson told The AP.Some of the study맥스카지노�s carefully chosen healthy volunteers, ages 18 to 55, will get higher dosages than others to test how strong the inoculations should be. Scientists will check for any side effects and draw blood samples to test if the vaccine is revving up the immune system, looking for encouraging clues like the NIH earlier found in vaccinated mice.맥스카지노�We don맥스카지노�t know whether this vaccine will induce an immune response, or whether it will be safe. That맥스카지노�s why we맥스카지노�re doing a trial,맥스카지노� Jackson stressed. 맥스카지노�It맥스카지노�s not at the stage where it would be possible or prudent to give it to the general population.맥스카지노�Most of the vaccine research under way globally targets a protein aptly named 맥스카지노�spike맥스카지노� that studs the surface of the new coronavirus and lets it invade human cells. Block that protein and people won맥스카지노�t get infected.Researchers at the NIH copied the section of the virus맥스카지노� genetic code that contains the instructions for cells to create the spike protein. Moderna encased that 맥스카지노�messenger RNA맥스카지노� into a vaccine.The idea: The body will become a mini-factory, producing some harmless spike protein. When the immune system spots the foreign protein, it will make antibodies to attack -- and be primed to react quickly if the person later encounters the real virus.That맥스카지노�s a much faster way of producing a vaccine than the traditional approach of growing virus in the lab and preparing shots from either killed or weakened versions of it.But because vaccines are given to millions of healthy people, it takes time to test them in large enough numbers to spot an uncommon side effect, cautioned Dr. Nelson Michael of the Walter Reed Army Institute of Research, which is developing a different vaccine candidate.맥스카지노�The science can go very quickly but, first, do no harm, right?맥스카지노� he told reporters last week.The Seattle research institute is part of a government network of centers that test all kinds of vaccines, and was chosen for the coronavirus vaccine study before COVID-19 began spreading widely in Washington state.Kaiser Permanente screened dozens of people, looking for those who have no chronic health problems and aren맥스카지노�t currently sick. Researchers aren맥스카지노�t checking whether would-be volunteers already had a mild case of COVID-19 before deciding if they맥스카지노�re eligible. If some did, scientists will be able to tell by the number of antibodies in their pre-vaccination blood test and account for that, Jackson said. Participants will be paid $100 for each clinic visit in the study.