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Researchers develop vaccine that could protect against Alzheimer's disease

Researchers develop vaccine that could protect against Alzheimer's disease
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Researchers develop vaccine that could protect against Alzheimer's disease
The University of New Mexico researchers have developed a vaccine that could prevent Alzheimer맥스카지노™s disease.Nicole Maphis and Kiran Bhaskar found that when the vaccine was given to mice, they developed antibodies that cleared tau protein, which in excess is a telltale sign of Alzheimer's, from their brains.The response to the vaccine lasted for months.맥스카지노œWe맥스카지노™re excited by these findings because they seem to suggest that we can use the body맥스카지노™s own immune system to make antibodies against these tangles," said Maphis, a student with UNM맥스카지노™s Biomedical Sciences Graduate Program. "And that these antibodies actually bind and clear these tau tangles.맥스카지노She and Bhaskar then tested the animals in a battery of maze-like tests.Mice that received the vaccination performed significantly better than those that hadn맥스카지노™t. MRI scans showed that the vaccinated animals had less brain shrinkage, signifying that the vaccine prevented neurons from dying. "These results confirm that targeting tau tangles using a vaccine intervention could rescue memory impairments and prevent neurons from dying," Maphis said.UNM scientists David Peabody and Bryce Chackerian created the vaccine.The two also helped create vaccines targeting dengue virus, hepatitis B and human papillomavirus, which is often present in the brains of Alzheimer's patients.In the future, Bhaskar said she wants to gain funding to commercialize this vaccine into creating an injection that could one day be tested in human patients with Alzheimer's.She said she is optimistic she'll receive funding for the vaccine from a federal Small Business Innovation Research grant to move forward with the research project.However, creating the drug could potentially cost millions of dollars and take decades.

The University of New Mexico researchers have developed a vaccine that could prevent Alzheimer맥스카지노™s disease.

Nicole Maphis and Kiran Bhaskar found that when the vaccine was given to mice, they developed antibodies that cleared tau protein, which in excess is a telltale sign of Alzheimer's, from their brains.

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The response to the vaccine lasted for months.

맥스카지노œWe맥스카지노™re excited by these findings because they seem to suggest that we can use the body맥스카지노™s own immune system to make antibodies against these tangles," said Maphis, a student with UNM맥스카지노™s Biomedical Sciences Graduate Program. "And that these antibodies actually bind and clear these tau tangles.맥스카지노

She and Bhaskar then tested the animals in a battery of maze-like tests.

Mice that received the vaccination performed significantly better than those that hadn맥스카지노™t. MRI scans showed that the vaccinated animals had less brain shrinkage, signifying that the vaccine prevented neurons from dying.

"These results confirm that targeting tau tangles using a vaccine intervention could rescue memory impairments and prevent neurons from dying," Maphis said.

UNM scientists David Peabody and Bryce Chackerian created the vaccine.

The two also helped create vaccines targeting dengue virus, hepatitis B and human papillomavirus, which is often present in the brains of Alzheimer's patients.

In the future, Bhaskar said she wants to gain funding to commercialize this vaccine into creating an injection that could one day be tested in human patients with Alzheimer's.

She said she is optimistic she'll receive funding for the vaccine from a federal Small Business Innovation Research grant to move forward with the research project.

However, creating the drug could potentially cost millions of dollars and take decades.