??? ???

1. GMP

(1) Good Manufacturing Practice (GMP) ???

GMP? ?? ??? ??? ?????? ???? ?? ????? ???? ????? ???? ??? ?????? ??, ??, ??? ?????? ? ??? ?? ??? ??? ??? ?? ????? ???? ??? ???.GMP? Good Manufacturing Practice? ????? ? ??? ??? ?? ???? ???.

(2) B-GMP? ??

B-GMP? ??? KGMP? ??? ??, KGMP? ????? ???, ?????? GMP, ? B-GMP? ??? ???, ?? ???? ??? ??? ????, WHO-GMP? ?? ???? ??. ????? ? ???.
???, B-GMP? 3???? ?? ??? 3? ?????, KGMP? ?? ???, ??? ????? ?? ????? ????.

2.????

(1)??? ??

??? ??? ?? ??? ?? ?? ?? ??? ??????? 1498?? Nuovo Receptario composito? ???? ????? ???? ???? ??? ?? 1498? ???? ??? ???? ??? ???. ? ? ???? ??? ???? ??? N¨¹rnberg ?? 1546? Valerius Cordus? ???? ??? Pharmacorum conficiendorum ratio, vocant Dispensatorium? ?????. ? ?? ??? ???? ?? ???? ???? ?????. ??? ??? ?? ?? ???, ??, ????, ??, ??? ? ? 50?? ???? ????? ?????. 1618?? ??? ?? ??(Pharmacopoeia Londinensis)? ?? ?? ??? London ? ???? ??? ? ???? ??? ??? ?? ?????. ??? ????? ??? ??(Danica)?? 1772?? ?????.